Endocrine Abstracts

Introduction: Hypoglycemia is the most frequent metabolic complication observed in patients with type 2 diabetes mellitus (T2DM). Moreover, rare insulinomas are the most common cause of endogenous hyperinsulinemic hypoglycemia in adults. The coincidence of insulinoma in a patient with pre-existing T2DM is an extremely rare condition and there are few case reports in the medical literature.Case report: A 76-year-old woman diagnosed with T2DM 6 years ago, ...

Introduction: The association of systemic lupus erythematosus (SLE) and dysthyroidism has been reported by several studies in a wide range of variability but studies focused on the influence of hypothyroidism on classic manifestations of SLE are scarce. Our purpose was to evaluate the prevalence of thyroid diseases in a cohort of SLE patients and the relevance of hypothyroidism with clinical and analytical parameters related to lupus.Methods/design: One ...

Introduction: Vitamin D deficiency is common among people living with HIV worldwide. There is a lack of studies focusing on prevalence and consequences of low levels of vitamin D in our health care area (south of Spain). The main aim of this study is to know the status of vitamin D and its consequences on parameters related to calcium metabolism in a cohort of patients with HIV infection in our area.Methods/Design: Cross-sectional study encompassing HIV-...

Introduction: Several studies have shown that BMI and visceral adiposity index (VAI) are inversely related to serum 25-hydroxy vitamin D (25OHD) in general population. There is a lack of studies performed in HIV population, whose body fat distribution is altered by lipodystrophy or liver disease. We aimed to analyze the cross-sectional associations of VAI and BMI with the 25OHD concentration and parameters related to calcium-phosphorus metabolism in HIV-infected patients.<...

Introduction: In our setting, it is quite common that control of major risk factors of patients with type 2 diabetes (T2D) after myocardial infarction (MI) is not made by specific risk factors units (SRFU). Here, we conducted a preliminary study to investigate the effects of a SRFU intervention on metabolic and cardiovascular outcomes in T2D patients who suffered from MI.Methods/design: This retrospective and observational study was performed in one sing...

Rationale: Secondary prevention of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM) has shown benefit but the level of control is still disappointing. Most of the results are documented within clinical trials. There isn’t enough information in routine clinical practice at short-term tracing. The main aim of this study is to collect information about the level of control of major risk factors in non-selected patients.Met...

Introduction: 25-Hydroxyvitamin D (25(OH)D) deficiency is a growing healthcare problem in HIV-infected patients. Evidence suggests that an optimal level of 25(OH)D would avoid secondary hyperparathyroidism but its optimal serum concentration has not been defined in HIV-infection. The aim of our study was to identify the 25(OH)D serum concentration that correlates to i-PTH increase and describe the prevalence of hypovitaminosis D in a cohort of HIV-infected patients.<p clas...

Introduction: Hypothyroidism is the most frequent thyroid disorder in patients with systemic lupus erythematosus (SLE) but the cause of this association is not well established. Moreover, no studies focused on the possible relationship between some specific immunologic patterns of SLE and the development of hypothyroidism have been reported.Methods: In our study, we determined the immunological features and the thyroid status of 103 consecutive patients ...

Rationale: Low level of vitamin D can results in secondary hyperparathyroidism (SH) that has been linked to increased cardiovascular risk in general population. However, the spectrum of cardiovascular risk associated with SH in HIV-infected adults remains uncertain. Our main aim was to determine its potential association with different markers of cardiovascular risk in HIV-infected adults.Methods: Cross-sectional study. Clinical data related to obesity, ...

Rationale: Type 2 diabetes mellitus (T2DM) is a well known independent prognosis factor associated with cirrhosis. Nevertheless, few studies are focused on the association between glucose metabolism and liver fibrosis in HCV/HIV patients and their conclusions are contradictory. The aim of our study was to investigate the relationship between glucose homeostasis and liver fibrosis in these patients.Methods: In a cross-sectional study, we compared prevalen...